First Presbyterian Church of Naples is located at 250 6th Street South, Naples, Florida 34102.

Head south on the Tamiami Trail (U.S. # 41).
Turn right at 1st Avenue S. Drive 0.3 mi.
Turn left at 6th Street S. Drive 0.1 mi.
The church is on the right.

From the Tamiami Trail (U.S. # 41) in Old Naples, turn into 5th Ave S. Drive 0.3 mi. and turn right at 6th Street S. The church will be on the left 0.2 mi.